Welcome to the International AIDS Society-USA Core Faculty

Research Topics

Pharmacokinetics of antiretroviral drugs
Methadone metabolism by cytochrome P450
Stereoselective azole metabolism

Lecture and Writing Topics

Drug-drug interactions with antiretroviral drugs
Cytochrome P450 metabolism of drugs
Pharmacokinetics of protease inhibitors and NNRTl

Current Professional Summary

Dr Gerber is a Professor of Medicine and Pharmacology at the University of Colorado Health Sciences Center and an Attending Physician in Infectious Diseases at University Hospital. He also teaches second- and fourth-year medical students as well as house staff in the field of infectious diseases and pharmacology.

Committees and Organizations

Metabolic Complications Guidelines Panel, IAS–USA
Member, AIDS Clinical Trial Group Pharmacology Committee
Western Association of Physicians
American Society for Clinical Pharmacology and Therapeutics
American Society for Pharmacology and Experimental Therapeutics

Honors and Awards

Named one of "The Best Doctors in America" (1994, 1996, 1997, 1998, 2000, 2003)
Burroughs Wellcome Scholar in Clinical Pharmacology (1985–1990)

Education

Queens College, BA (1968)
Medical College of Virginia, MD (1972)
Medical College of Virginia, Resident in Medicine (1974–1976)
Vanderbilt University, Fellow in Clinical Pharmacology (1976–1978)
University of Colorado Health Sciences Center, Fellow in Infectious Diseases (1993–1994)

Selected Publications

Gerber JG, Rosenkranz S, Segal Y, Aberg J, D'Amico R, Mildvan D, Gulick R, Hughes V, Flexner C, Aweeka F, Hsu A, Gal J; ACTG 401 Study Team. Effect of ritonavir/saquinavir on stereoselective pharmacokinetics of methadone: results of AIDS Clinical Trials Group (ACTG) 401. J Acquir Immune Defic Syndr. 2001;27:153-160.
Fichtenbaum CJ, Gerber JG, Rosenkranz SL, Segal Y, Aberg JA, Blaschke T, Alston B, Fang F, Kosel B, Aweeka F; NIAID AIDS Clinical Trials Group. Pharmacokinetic interactions between protease inhibitors and statins in HIV seronegative volunteers: ACTG Study A5047. AIDS. 2002;16:569-577.
Pereira AS, Smeaton LM, Gerber JG, Acosta EP, Snyder S, Fiscus SA, Tidwell RR, Gulick RM, Murphy RL, Eron JJ Jr. The pharmacokinetics of amprenavir, zidovudine, and lamivudine in the genital tracts of men infected with human immunodeficiency virus type 1 (AIDS clinical trials group study 850). J Infect Dis. 2002;186:198-204.
Hamzeh FM, Benson C, Gerber J, Currier J, McCrea J, Deutsch P, Ruan P, Wu H, Lee J, Flexner C; AIDS Clinical Trials Group 365 Study Team. Steady-state pharmacokinetic interaction of modified-dose indinavir and rifabutin. Clin Pharmacol Ther. 2003;73:159-169.
Dilmaghanian S, Gerber JG, Filler SG, Sanchez A, Gal J. Enantioselectivity of inhibition of cytochrome P450 3A4 (CYP3A4) by ketoconazole: Testosterone and methadone as substrates. Chirality. 2004;16:79-85.
Gerber JG, Rhodes RJ, Gal J. Stereoselective metabolism of methadone N-demethylation by cytochrome P4502B6 and 2C19. Chirality. 2004;16:36-44.