Physician Education: Bridging Clinical Research and Patient Care

Faculty Profile

Director, Program in Nutritional Metabolism
Professor, Harvard Medical School
Boston, Massachusetts

Topics of Professional Interest:
  • The AIDS wasting syndrome
  • Lipid management in the HIV lipodystrophy syndrome
  • HIV lipodystrophy
  • Disorders of insulin and glucose metabolism in HIV
  • Metabolic complications of HIV disease
Current Professional Summary:

Dr Grinspoon is a Clinical Researcher at the Neuroendocrine Unit of Massachusetts General Hospital in Boston, and an Assistant Professor of Medicine at Harvard Medical School.

Committees and Organizations:
Honors and Awards:
  • Editorial Board, Journal of Clinical Endocrinology and Metabolism
  • NIH NCRR & NIDDK Study Sections
  • Health and Human Services Panel on Nutrition Guidelines in HIV
  • Cornell University, BA (1983)
  • University of Rochester School of Medicine, MD (1988)
  • Columbia Presbyterian Hospital, Internal Medicine Residency (1988–1992)
  • Massachusetts General Hospital, Endocrine Fellowship (1992–1995)
Selected Publications:
  1. Loss of lean body and muscle mass correlates with androgen levels in hypogonadal men. J Clin Endocrinol Metab.
  2. Body composition and endocrine function in women with AIDS wasting. J Clin Endocrinol Metab.
  3. Effects of androgen administration in men with AIDS wasting syndrome: a randomized, placebo-controlled trial. Ann Intern Med.
  4. Fasting hyperinsulinemia and changes in regional body composition in HIV-infected women. J Clin Endocrinol Metab.
  5. Fasting hyperinsulinemia in HIV-infected men: relationship to body composition, gonadal function and protease inhibitor use. J Clin Endocrinol Metab.
  6. Metformin use in the HIV lipodystrophy syndrome: a randomized, controlled trial. JAMA.
  7. Metabolic abnormalities and cardiovascular disease risk factors in HIV-infected men and women with the lipodystrophy syndrome. Clin Infect Dis.
  8. Increased PAI-1 and tPA antigen levels are reduced with metformin therapy in HIV-infected patients with fat redistribution and insulin resistance. J Clin Endocrinol Metab.
  9. Assessment of growth hormone dynamics in the HIV lipodystrophy syndrome. J Clin Endocrinol Metab.
  10. Transdermal testosterone administration in women with AIDS wasting: a pilot study. J Clin Endocrinol Metab.


Improving the Management of HIV Disease®: An Advanced CME Live Course in HIV Pathogenesis, Antiretrovirals, and Other Selected Issues in HIV Disease Management

An Advanced CME Live Course in HIV Pathogenesis, Antiretrovirals, and Other Selected Issues in HIV Disease Management