Annie F. Luetkemeyer, MD

A. Doxycycline should not be given with ritonavir-boosted HIV protease inhibitors

B. Doxycycline may protect against mpox

C. Doxycycline should not be given with tenofovir-containing HIV preexposure prophylaxis

D. Doxycycline should not be taken at the same time as bivalent-containing antacids, multivitamins, or calcium supplements

E. Doxycycline should not be taken with acid-blocking medications like proton-pump inhibitors and histamine-2 blockers