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David Grelotti, MD
David Grelotti, MD
University of California San Diego
San Diego, CA
CROI
Conference on Bacteriophages
RWHAP CLINICAL CONFERENCE
Podcasts
Slides
Question of the Week
Guidelines
Contact
CME Courses
HIV In-Person and Virtual Courses
Current On-Demand Courses
About Courses
CME Webinars
Upcoming Webinars
Current On-Demand Webinars
MATE Act CME
About Webinars
Dialogues
Upcoming IAS–USA Dialogues: Emerging Infections and Health Threats
On-Demand Dialogues
About Dialogues
Topics In Antiviral Medicine
Current Issues for CME
Previous Issues
TAM
Policies and Practices
Permission Request Form
HIV Drug Resistance
HIV Drug Resistance Resources
HIV Drug Resistance Mutations Chart
Recent Webinars
Journal Articles
Fellow Resources
Resources for Fellows and Others New to the HIV Field
On-Demand Webinars for Fellows
IAS-USA Guidelines and Recommendations
On-Demand Webcasts
Research Collaborations
Additional Resources
About
Scientific Leadership Board
IAS-USA Leadership Award Recipients
Core Faculty
Mission
Staff
CME
Funding Information
Careers
Website Policies
Discrimination and Harassment Policy
Governance
Suggestions and Recommendations from San Francisco Locals
Donate
FAQs
Practice Question of the Week
July 14, 2026: Evaluation of Persistent Diarrhea and Fatigue
A 57-year-old woman with HIV (CD4+ count, 110 cells/µL) presents to care with 3 weeks of watery diarrhea, fatigue, and a 10 lb weight loss. She reports eating several prepackaged salads but has not traveled internationally. Routine bacterial stool cultures are within reference ranges. Which of the following is the most appropriate next step?
A. Initiate empiric ciprofloxacin 500 mg orally twice daily for 7 days
B. Order a specific stool modified acid-fast stain for Cyclospora cayetanensis
C. Order a specific stool polymerase chain reaction (PCR) test for norovirus
D. Reassure the patient that the illness is likely self-limited and will resolve without treatment
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