Jonathan Koff, MD

A. A recent analysis in Africa integrated HIV preexposure prophylaxis (PrEP) and postexposure prophylaxis (PEP) choices with self-assessed risk for HIV acquisition. It showed poor adherence and cost-effectiveness in that setting

B. Analysis of HIV prevention studies over the past 15 years suggests that HIV incidence has declined substantially

C. Doxycycline PrEP substantially decreases risk for syphilis and chlamydia, with no significant increase in tetracycline-resistant Neisseria, Staphylococcus, or Streptococcus

D. Stool testing improves the yield of tuberculosis diagnostic testing

Jonathan Koff, MD

Jonathan Koff, MD

Yale University

New Haven, CT, USA

January 13, 2026: HIV Prevention and Coinfections