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Marina Klein, MD, MS
Marina Klein, MD, MS
Professor of Medicine
McGill University
Montreal, QC, Canada
CROI
Conference on Bacteriophages
RWHAP Clinical Conference
Podcasts
Slides
Question of the Week
Donate
Contact
CME Courses
HIV In-Person and Virtual Courses
Current On-Demand Courses
About Courses
CME Webinars
Upcoming Webinars
Current On-Demand Webinars
MATE Act CME
About Webinars
Dialogues
Upcoming IAS–USA Dialogues
On-Demand Dialogues
About Dialogues
Topics In Antiviral Medicine
Current Issues for CME
Previous Issues
TAM
Policies and Practices
Permission Request Form
HIV Drug Resistance
Drug Resistance Mutations Chart
Recent Webinars
Journal Articles
Fellow Resources
Fellow Resources
IAS-USA Guidelines and Recommendations
On-Demand Webcasts
Research Collaborations
Additional Resources
About
Scientific Leadership Board
IAS-USA Leadership Award Recipients
Core Faculty
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Staff
CME
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FAQs
Practice Question of the Week
May 12, 2025: Management of Antimicrobial Resistant Gonorrhea
A 42-year-old heterosexual man presents to the clinic with a 4-day history of urethral discharge and dysuria. He reports having sexual intercourse with a woman 3 days prior to symptom onset while he was traveling in Thailand. He has genital discharge, which shows Gram-negative diplococci on stain. Which of the following is the most appropriate next step in management?
A. Send urine for Neisseria gonorrhoeae/Chlamydia trachomatis nucleic-acid amplification testing (NAAT), and treat with ceftriaxone 500 mg intramuscularly once
B. Send urine for Neisseria gonorrhoeae/Chlamydia trachomatis NAAT, and treat with ceftriaxone 1 g intramuscularly once and azithromycin 1 g orally once
C. Send urine for Neisseria gonorrhoeae/Chlamydia trachomatis NAAT, send urine for gonococcal culture, and treat with ceftriaxone 500 mg intramuscularly once and doxycycline 100 mg orally twice per day for 7 days
D. Send urine for Neisseria gonorrhoeae/Chlamydia trachomatis NAAT, send urethral swab for gonococcal culture, and treat with ceftriaxone 500 g intramuscularly once and doxycycline 100 mg orally twice per day for 7 days
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