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Nichole Klatt, PhD

Nichole Klatt, PhD

University of Minnesota

Professor, Division Chief
Division of Surgical Outcomes and Precision Medicine Research
University of Minnesota
Minneapolis, Minnesota

131 Steuart St, Suite 500, San Francisco, CA 94105

Phone: (415) 544-9400 | info@iasusa.org

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Practice Question of the Week

May 23, 2022: Treating Depression in People With HIV

A 38-year-old man diagnosed with HIV comes to the office expressing passive suicidal ideation. During the past 6 weeks, he has experienced fatigue, loss of interest in usual activities, a 7-kg (15-lb) weight loss, and insomnia. He is diagnosed with a major depressive episode. Which of the following is NOT true regarding his depression treatment?
- A. Beginning a low dose of antidepressant reduces the risk of adverse effects
- B. Escalating the dose of an antidepressant medication should be avoided
- C. Accepting treatment with antidepressants is associated with greater adherence to antiretroviral medications
- D. More than one antidepressant trial may be needed to achieve remission from depression

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