Yvonne Maldonado, MD

A. Most participants with inconclusive serologic results had detectable HIV-1 RNA by ultrasensitive single-copy assay (SCA), confirming acute HIV infection

B. All participants with inconclusive serologic results had confirmed HIV infection by Geenius HIV 1/2 Supplemental Assay and were transitioned to antiretroviral therapy

C. No participant with inconclusive serologic results had detectable HIV-1 by ultrasensitive SCA

D. Inconclusive serologic results occurred primarily because HIV RNA testing was not incorporated into the study protocol after CAB-LA initiation

Yvonne Maldonado, MD

Yvonne Maldonado, MD

Professor of Pediatrics (Infectious Disease) and of Epidemiology and Population Health

Stanford University

Palo Alto, CA

August 10, 2026: HIV Diagnostic Challenges in Individuals Taking Long-Acting Cabotegravir PrEP