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CROI 2014: Abstracts 1-1068
CROI 2014: Abstracts 1-1068
CROI
Conference on Bacteriophages
RWHAP CLINICAL CONFERENCE
Podcasts
Slides
Question of the Week
Guidelines
Contact
CME Courses
HIV In-Person and Virtual Courses
Current On-Demand Courses
About Courses
CME Webinars
Upcoming Webinars
Current On-Demand Webinars
MATE Act CME
About Webinars
Dialogues
Upcoming IAS–USA Dialogues: Emerging Infections and Health Threats
On-Demand Dialogues
About Dialogues
Topics In Antiviral Medicine
Current Issues for CME
Previous Issues
TAM
Policies and Practices
Permission Request Form
HIV Drug Resistance
HIV Drug Resistance Resources
HIV Drug Resistance Mutations Chart
Recent Webinars
Journal Articles
Fellow Resources
Resources for Fellows and Others New to the HIV Field
On-Demand Webinars for Fellows
IAS-USA Guidelines and Recommendations
On-Demand Webcasts
Research Collaborations
Additional Resources
About
Scientific Leadership Board
IAS-USA Leadership Award Recipients
Core Faculty
Mission
Staff
CME
Funding Information
Careers
Website Policies
Discrimination and Harassment Policy
Governance
Suggestions and Recommendations from San Francisco Locals
Donate
FAQs
Practice Question of the Week
November 2, 2026: Assessment of Neurologic Findings After ART Initiation
A woman in her 30s with HIV (CD4+ count, 16 cells µL) has been diagnosed with pulmonary tuberculosis and is on rifampin, isoniazid, pyrazinamide, and ethambutol (RIPE) therapy. She initiated daily tenofovir alafenamide/emtricitabine and twice daily dolutegravir 10 days ago and now presents with fevers and new onset vertical nystagmus. Laboratory values support antiretroviral therapy (ART) adherence with plasma HIV RNA level below the limit of detection. Repeat sputum smear and cultures are negative, and chest computed tomography scan shows improvement. Magnetic resonance imaging of the brain shows an enhancing medullary lesion. Which of the following statements is TRUE?
A. Treatment with prednisone will improve her survival
B. Evaluation should start with a lumbar puncture, serum cryptococcal antigen (CrAg), and Toxoplasma gondii serology
C. Evaluation should start with a fluorodeoxyglucose positron emission tomography (FDG-PET) scan
D. Given that she has an HIV RNA level below the limit of detection, it is unlikely that this represents a new opportunistic infection
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