Michael T. Laub, PhD
Massachusetts Institute of Technology
Salvador E. Luria Professor of Biology
Cambridge, MA
Dr Laub’s research currently focuses on phage-bacteria interactions with a particular emphasis on the antiphage defense mechanisms used by bacteria to defend themselves against phages and the counterdefense mechanisms employed by phages. We use a variety of genetic and computational tools to identify new antiphage defense systems in E. coli, B. subtilis, and S. aureus. The mechanistic basis of immunity provided by individual systems is pursued using a combination of genetics, biochemistry, cell biology, and structural approaches. The lab also examines the tempo, modes, and patterns of genome evolution in bacteria and phages that stems from their constant battle with each other.
(Updated July 18, 2024)
Karen Maxwell, PhD
University of Toronto
Professor
Toronto, ON, Canada
Dr Maxwell completed her PhD in Molecular Genetics at the University of Toronto, where she worked in Dr. Marvin Gold’s lab studying the assembly of bacteriophage lambda. Her postdoctoral work was done at the Ontario Centre for Structural Genomics where she led a project focused on phage structural genomics. She then moved to a Research Associate position at the Donnelly Centre, University of Toronto before starting in the Department of Biochemistry as an Assistant Professor in 2016.
(Updated July 18, 2024)