Episode 45 – Bacteriophages for the Treatment of Antimicrobial-resistant (AMR) Bacterial Infections with Dr Graham F. Hatfull
In this episode of Going anti-Viral, Dr Michael Saag speaks with Dr Graham Hatfull, a Professor of Biological Sciences at the University of Pittsburgh. Dr Hatfull joins Dr Saag to discuss Bacteriophages for the treatment of antimicrobial-resistant (AMR) bacterial infections. Dr Hatfull provides an overview of the types of bacteriophages and how they can be used to treat antimicrobial-resistant bacteria. Dr Hatfull and Dr Saag discuss the challenges of treating bacterial infections with phages, given the diversity and complexity of the different types of bacteria, and bringing phage treatments to scale. Finally, they discuss what future research is needed to overcome the challenges of phage treatment and look to the future where technology enables synthetically produced phages to provide targeted therapy to antimicrobial resistant bacteria.
Resources:
- Episode 10 – Harnessing the Power of Bacteriophages With Dr Robert Schooley:
- Exploring Bacteriophage Therapy for Drug-Resistant
- Bacterial Infections Robert T. Schooley, MD: https://www.iasusa.org/wp-content/uploads/2023/03/31-1-23.pdf
- The inaugural Conference on Bacteriophages: Biology, Dynamics, and Therapeutics:https://www.iasusa.org/bacteriophage-conference/
Episode 10 – Harnessing the Power of Bacteriophages With Dr Robert Schooley
In this podcast episode, host Dr Michael Saag speaks with Dr Robert “Chip” Schooley, a distinguished Professor of Medicine in the Division of Infectious Diseases and Global Public Health at the University of California San Diego. They discuss the revolutionary potential of bacteriophages, viruses that can infect and kill bacteria. They detail the research efforts and case studies involved in understanding the potential deployment of bacteriophages as a medical treatment. The discussion also highlights the necessity for clinical trials and future research involving genetically engineered phages.
Bacteriophage Therapy: The Enemy of My Enemy is My Friend
Presenter: Robert T. Schooley, MD
August 17, 2021
10:00 AM – 11:15 AM PT
Learning Objectives
On completion of this activity, learners will be able
- Describe the important advancements in bacteriophage therapeutics
- Describe the potential applications of bacteriophage therapeutics in clinical practice
Exploring Bacteriophage Therapy for Drug-Resistant Bacterial Infections
Author: Robert T. Schooley, MD
From Topics in Antiviral Medicine
Volume 31, Issue 3