Basics of HIV Drug Resistance Mutations

Basics of HIV Drug Resistance Mutations


Francesca Ceccherini Silberstein, PhD
University of Rome Tor Vergata
Rome, Italy
Douglas D. Richman, MD
University Of California San Diego
La Jolla, CA
Robert W. Shafer, MD
Stanford University
Stanford, CA


December 14, 2022 - 10:00 AM


December 14, 2022 - 11:30 AM

Add to iCal Calendar

This is the rescheduled date for our postponed October 27, 2022, webinar. If you have previously registered for the prior date, your registration has automatically been converted.


Assessment of Needs

This webinar will review the basic principles of HIV drug resistance mutations and highlight the recent IAS–USA 2022 Update of the Drug Resistance Mutations in HIV-1, released in September 2022. It will provide an overview of the article, particularly on understanding and applying the information in clinical practice. Additionally, it will discuss the recent update, including new drugs such as lenacapavir and doravirine, and how to manage drug resistance in patients.

Learning Objectives

Upon completion of this activity, learners will be able to:

  • Describe basic principles of HIV drug resistance mutations
  • Explain how to understand and interpret the information presented on the IAS–USA 2022 Update of the Drug Resistance Mutations in HIV-1
  • Identify recent updates to the IAS–USA 2022 Update of the Drug Resistance Mutations in HIV-1 and how they apply to the management of drug resistance in patients


Who Should Attend

This webinar is designed for clinical decision makers who are actively involved in HIV care and research, including physicians, physician assistants, nursing professionals, pharmacists, and other health care professionals.

Individual registration is required in order to receive CME credit or a certificate of participation.

Registration closes on December 14, 2022, 10:30 AM (PT).

Certificates will be available after the completion of the evaluation and claim form.

For more information or questions, please contact the registration department at or 415-544-9400.

Conflicts of Interest

In the interest of maintaining the independence of its continuing medical education (CME) activities, the International Antiviral Society–USA (IAS–USA) requires all persons with control of educational content (eg, faculty, Scientific Leadership Board, Governance Board, and program planner) to disclose any financial relationships with ineligible companies (previously defined as “commercial interests”) that they have had within the past 24 months. Any real or apparent conflicts of interest of those parties are resolved and mitigated prior to the CME activity being delivered. Individuals who refuse to disclose financial interests may not participate in IAS–USA CME activities.  

The Accreditation Council for Continuing Medical Education (ACCME) defines ineligible companies as “those whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.” 

IAS–USA will identify and resolve ahead of time any possible conflicts of interest that may influence CME activities with regard to exposition or conclusion. Information about financial relationships with ineligible companies for the presenter and planners/reviewers is below and in the slides prior to the presentation of educational content. 


Dr Ceccherini-Silberstein has been a consultant to Gilead Sciences, Inc, Merck Sharp & Dohme, Inc, Theratechnologies, Inc, ViiV Healthcare, and has received research grants from Gilead Sciences, Inc, Merck Sharp & Dohme, Inc., and ViiV Healthcare (Updated 12/14/22)

Dr Richman has served on a scientific advisory board for Antiva Biosciences, Assembly Biosciences, Inc., Generate Biomedicines, IGM Biosciences, Inc., and serves as Chair of the Data Management Committee of Gilead Sciences, Inc. (Updated 12/14/22)

Dr Shafer has served on advisory boards for Gilead Sciences, GlaxoSmithKline, and Vir Biotechnology. He has received payment for lectures from Gilead Sciences, ViiV Healthcare, and GlaxoSmithKline. (Updated 12/14/22)


Planner/Reviewer 1 has no relevant financial relationships with ineligible companies to disclose. (12/14/22)
Planner/Reviewer 2 has no relevant financial relationships with ineligible companies to disclose. (12/14/22)


CME Credits

The International Antiviral Society–USA (IAS–USA) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The IAS–USA designates this live activity for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


ABIM MOCSuccessful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.5 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. IAS-USA, the CME activity provider, will submit your participant information (eg, name, date of birth, activity credits earned, ABIM MOC number) to ABIM through the PARS system for the purpose of reporting ABIM MOC credits.

Nursing Credits

Educational Review Systems is an approved approver of continuing nursing education by the Alabama State Nursing Association, an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation.  Provider # 5-115.  This program is approved for 1.5 hours of continuing nursing education.

Educational Review Systems is also approved for nursing continuing education by the state of California (Provider # 14692), the state of Florida and the District of Columbia.

Pharmacy Credits

Accreditation Council for Pharmacy Education logo Educational Review Systems is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education.   Participants of the session who complete the evaluation and provide accurate NABP e-Profile information will have their credit for 1.5 contact hours (0.15 CEU) submitted to CPE Monitor as early as 14 days after the event and no later than 60 days after the event.  Please know that if accurate e-Profile information is not provided within 60 days of the event, credit cannot be claimed after that time.  The participant is accountable for verifying the accurate posting of CE credit to their CPE Monitor account within 60 days.
UAN  # 0761-9999-22-454-L02-P

Grant Support

This activity is part of the IAS–USA national educational effort that is funded, in part, by charitable contributions from ineligible companies. Per IAS–USA policy, any effort that uses grants from ineligible companies must receive grants from several companies with competing products. Funds are pooled and distributed to activities at the sole discretion of the IAS–USA. Grantors have no input into any activity, including its content, development, or selection of topics or speakers. Generous support for this activity has been received from the following contributors.


Gilead Sciences, Inc.
Merck & Co, Inc.
ViiV Healthcare


Janssen Therapeutics


Theratechnologies, Inc.


Frequently Asked Questions

View our list of FAQs about attending a webinar.

Further Questions?
Please contact the registration department at or 415-544-9400.